Sharing Data. Building Knowledge. Improving Care.

ClinGen is dedicated to building an authoritative central resource that defines the clinical relevance of genes and variants for use in precision medicine and research.  Learn more about our organization and our ongoing efforts below.

ClinGen Receives Recognition Through New FDA Human Variant Database Program

The ClinGen expert curated variants are available for unrestricted use in the community via ClinVar, an archive which is funded and maintained by NIH’s National Center for Biotechnology Information, part of the National Library of Medicine.

Human Mutation Special Issue: ClinGen and ClinVar – Enabling Genomics in Precision Medicine

The November 2018 issue of Human Mutation is dedicated to papers relating to the activities of the National Institutes of Health‐supported Clinical Genome Resource Program and the ClinVar database supported by the National Center for Biotechnology Information. 

Volunteer to Curate

Interested in volunteering to curate for ClinGen? Please take this brief survey to tell us more about your interests, expertise, and desired level of involvement so we can pair you with an appropriate curation activity and/or Expert Panel. 

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@ClinGenResource On Twitter

RT @GenomeConnect: If you haven’t read our recent paper in Human Mutation, check it out! Free access until February! #genomeconnect #datash… - 1 week ago
The new online form in the #ClinVar Submission Portal, the Single SCV Update, will be an incredibly useful tool for…… - 3 weeks ago
RT @NCBI_Clinical: #ClinVar has >50K variants submitted by @AmbryGenetics:… - 1 month ago
RT @NCBI_Clinical: Find more than 133,000 variant interpretations from @Invitae in #ClinVar:… - 1 month ago