Clinical Domain Working Groups
Myeloid Malignancy Variant Curation Expert PanelMembership Documents
This Expert Panel co-supported by ASH will curate variants in genes associated with inherited risk for myeloid malignancies. This panel will consider variants in genes that cause life-long thrombocytopenia (e.g., RUNX1, ANKRD26, GATA2 and ETV6) as well as those associated only with cancer risk (e.g., DDX41 and CEBPA).
Expert Panel Status
ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variantsPublications - October 22, 2019
ClinGen Myeloid Malignancy Expert Panel Specifications to the ACMG/AMP Variant Interpretation Guidelines Version 1Curation Activity Procedures - July 10, 2019
Myeloid Malignancy Variant Curation Expert Panel COIConflict Of Interest (COI) - March 26, 2019
Expert Panel Membership
Membership spans many fields, including genetics, medical, academia, and industry.