The following documents and presentations are available to help people learn and understand the variant curation process, as well as ClinGen's efforts to modify ACMG variant assessment criteria.  For questions about existing materials or requests for new materials, contact us at

Modifying the BA1 population allele frequency criterion

Poster from ASHG 2016 describing efforts of the Sequence Variant Interpretation working group.

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Resolving Inter-Laboratory Discrepancies in ClinVar

Poster from ACMG 2016 describing efforts to reduce the number of interpretation conflicts between laboratories in ClinVar.

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Variant Interpretation and the ClinGen Curation Interface Tool

Presentaiton by Steven Harrison, PhD from the 2018 Interpreting Genomes for Rare Disease course.

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