We recommend all potential ClinVar submitters discuss their sharing plans with their local IRB (if applicable).  Depending on the type(s) of data being submitted, some IRBs may consider the project exempt, while others may require a more detailed review. Please use the following materials to assist you in preparing your IRB submission.  

If your laboratory is not affiliated with an IRB (such as a commercial laboratory) - please contact us at clingen@clinicalgenome.org for additional information. Geisinger Health System may be able to serve as your IRB of record.

If you need additional help, please contact clingen@clinicalgenome.org

Sample Protocols

Below are a variety of different types of protocol templates.  Choose the one that best represents the type of data you'd like to submit, or mix and match parts from several to suit your needs.